7a-Hydroxyfrullanolide

• CAT Number: C000824
• CAS Number: 105578-87-8
• Molecular Formula: C₁₅H₂₀O₃
• Molecular Weight: 248.32
• Purity: ≥95%
• Synonyms: 3-methylenenaphtho[1,2-b]furan-2(3H)-one
• Solubility: Chloroform (Slightly), Methanol (Slightly), Acetone
• Appearance: Pale Yellow to Beige Sticky Solid
• Storage: -78°C, Hygroscopic
• IUPAC Name: (3aR,5aR,9bS)-3a-hydroxy-5a,9-dimethyl-3-methylidene-4,5,6,7,8,9b-hexahydrobenzo[g][1]benzofuran-2-one
• InChI: InChI=1S/C15H20O3/c1-9-5-4-6-14(3)7-8-15(17)10(2)13(16)18-12(15)11(9)14/h12,17H,2,4-8H2,1,3H3/t12-,14+,15+/m0/s1
• InChIKey: XMPDAVDYIOMTLX-NWANDNLSSA-N
• SMILES: CC1=C2[C@H]3[C@@](CC[C@]2(CCC1)C)(C(=C)C(=O)O3)O

7α-Hydroxyfrullanolide（Cat No.:C000824）is a natural sesquiterpene lactone isolated from certain plant species, known for its bioactive properties. It belongs to a class of compounds with anti-inflammatory, antimicrobial, and anticancer activities. The compound has been studied for its potential therapeutic applications, particularly in modulating inflammatory pathways and inhibiting tumor cell proliferation. 7α-Hydroxyfrullanolide’s structure, which includes a lactone ring, contributes to its bioactivity by interacting with cellular signaling pathways. While preclinical studies show promise, further research is needed to better understand its mechanism of action and evaluate its safety and efficacy in clinical settings.

Reference

Sangsopha, Watchara, et al.: Phytochemistry Letters,В 17,В 278-281В (2016); Fonseca, Lyle C., et al.: Euro. J. of Pharmaco.,В 644(1-3),В 220-229 (2010); Chakrabarti, Debarshi, et al.: Pharmaco. & Pharm.,В 3(2),В 178-194 (2012)