8-Anilino-1-naphthalenesulfonic Acid

For research use only. Not for therapeutic Use.

  • CAT Number: R064352
  • CAS Number: 82-76-8
  • Molecular Formula: C16H13NO3S
  • Molecular Weight: 299.344
  • Purity: ≥95%
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1,8-<wbr></wbr>ANS is a fluorescent dye that binds with high affinity to hydrophobic surfaces of proteins. The emission maximum of 1,8-<wbr></wbr>ANS undergoes a blue shift and fluorescence intensity increases significantly upon binding to low polarity regions of a protein surface. These properties make 1,8-<wbr></wbr>ANS well suited for determining the affinity of hydrophobic ligands to their corresponding binding proteins, such as the binding of free fatty acids to fatty acid binding proteins (FABPs). 1,8-<wbr></wbr>ANS binds to intestinal FABP (FABP2) with a K<sub>d</sub> value of ~9.7 µM at 24.5°C.


Catalog Number R064352
CAS Number 82-76-8
Synonyms

1-(Phenylamino)-8-naphthalenesulfonic Acid; 1-Anilino-8-naphthalenesulfonic Acid; 8-(Phenylamino)-1-naphthalenesulfonic Acid; 8-Anilino-1-naphthalenesulfonate; ANS;?ANS (Fluorescent Probe); NSC 1746; Phenyl Peri Acid

Molecular Formula C16H13NO3S
Purity ≥95%
Storage -20°C
IUPAC Name 8-anilinonaphthalene-1-sulfonic acid
InChI InChI=1S/C16H13NO3S/c18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13/h1-11,17H,(H,18,19,20)
InChIKey FWEOQOXTVHGIFQ-UHFFFAOYSA-N
SMILES C1=CC=C(C=C1)NC2=CC=CC3=C2C(=CC=C3)S(=O)(=O)O

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