For research use only. Not for therapeutic Use.
8-Bromo-2′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Catalog Number | R041612 |
| CAS Number | 14985-44-5 |
| Synonyms | (2R,5R)-5-(6-amino-8-bromopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol |
| Molecular Formula | C10H12BrN5O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C10H12BrN5O3/c11-10-15-7-8(12)13-3-14-9(7)16(10)6-1-4(18)5(2-17)19-6/h3-6,17-18H,1-2H2,(H2,12,13,14)/t4?,5-,6-/m1/s1 |
| InChIKey | NJBIVXMQFIQOGE-YSLANXFLSA-N |
| SMILES | C1C(C(OC1N2C3=NC=NC(=C3N=C2Br)N)CO)O |
| Reference | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
