For research use only. Not for therapeutic Use.
8-Epidiosbulbin E acetate（Cat No.:I018208）is a bioactive compound derived from Euphorbia species, particularly noted for its potent anti-inflammatory and anticancer properties. This compound acts as a modulator of various signaling pathways, including those involved in cell proliferation and apoptosis. 8-Epidiosbulbin E acetate has been studied for its ability to induce tumor cell death and inhibit tumor growth, making it a potential candidate for cancer therapy. Additionally, its anti-inflammatory effects suggest possible therapeutic applications in treating chronic inflammatory diseases. Ideal for biochemical and pharmacological research, it offers a valuable tool for exploring novel therapeutic strategies.
| Catalog Number | I018208 |
| CAS Number | 91095-48-6 |
| Molecular Formula | C₂₁H₂₄O₇ |
| Purity | ≥95% |
| Target | Anti-infection |
| Storage | Store at -20°C |
| IUPAC Name | [(1R,2S,3S,5S,8S,10S,11R,13R)-8-(furan-3-yl)-10-methyl-6,15-dioxo-7,14-dioxatetracyclo[11.2.1.02,11.05,10]hexadecan-3-yl] acetate |
| InChI | InChI=1S/C21H24O7/c1-10(22)26-16-7-15-20(24)28-17(11-3-4-25-9-11)8-21(15,2)14-6-12-5-13(18(14)16)19(23)27-12/h3-4,9,12-18H,5-8H2,1-2H3/t12-,13+,14+,15+,16-,17-,18+,21-/m0/s1 |
| InChIKey | DYSOIAQEKRDXRB-GFTCARDDSA-N |
| SMILES | CC(=O)O[C@H]1C[C@@H]2C(=O)O[C@@H](C[C@]2([C@H]3[C@H]1[C@H]4C[C@@H](C3)OC4=O)C)C5=COC=C5 |
| Reference | [1]. Shriram V, et al. A potential plasmid-curing agent, 8-epidiosbulbin E acetate, from Dioscorea bulbifera L. against multidrug-resistant bacteria. Int J Antimicrob Agents. 2008 Nov;32(5):405-10.<br>[2]. Lin D, et al. Role of Metabolic Activation in 8-Epidiosbulbin E Acetate-Induced Liver Injury: Mechanism of Action of the Hepatotoxic Furanoid. Chem Res Toxicol. 2016 Mar 21;29(3):359-66. |
