8-Hydroxy Mianserin-d3

• CAT Number: R008206
• CAS Number: 1215316-77-0
• Molecular Formula: C18H20N2O
• Molecular Weight: 283.389
• Purity: ≥95%
• Synonyms: 1,2,3,4,10,14b-Hexahydro-2-(methyl-d3)-dibenzo[c,f]pyrazino[1,2-a]azepin-8-ol; 8-Hydroxymianserin-d3
• Storage: Store at +4C
• IUPAC Name: 5-(trideuteriomethyl)-2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8(13),9,11,15,17-hexaen-11-ol
• InChI: InChI=1S/C18H20N2O/c1-19-8-9-20-17-5-3-2-4-13(17)10-14-11-15(21)6-7-16(14)18(20)12-19/h2-7,11,18,21H,8-10,12H2,1H3/i1D3
• InChIKey: IDQNTICZJWERCI-FIBGUPNXSA-N
• SMILES: [2H]C([2H])([2H])N1CCN2C(C1)C3=C(CC4=CC=CC=C42)C=C(C=C3)O

8-Hydroxy Mianserin-d3 is a deuterated form of 8-hydroxy mianserin, a metabolite of mianserin, which is an antidepressant with serotonin and norepinephrine reuptake inhibitor properties. The three deuterium atoms replace hydrogen atoms in the molecule, providing a stable isotopic label that facilitates precise tracking in pharmacokinetic and metabolic studies. This labeled compound is used to study the metabolism, distribution, and excretion of mianserin and its metabolites. Its applications are significant in understanding drug metabolism, optimizing therapeutic strategies, and improving the safety profile of antidepressant treatments.