8-Hydroxyadenosine

• CAT Number: I042661
• CAS Number: 29851-57-8
• Molecular Formula: C10H13N5O5
• Molecular Weight: 283.24
• Purity: ≥95%
• Synonyms: 6-amino-9-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7H-purin-8-one
• IUPAC Name: 6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7H-purin-8-one
• InChI: InChI=1S/C10H13N5O5/c11-7-4-8(13-2-12-7)15(10(19)14-4)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H,14,19)(H2,11,12,13)/t3-,5-,6-,9-/m1/s1
• InChIKey: UEHOMUNTZPIBIL-UUOKFMHZSA-N
• SMILES: C1=NC(=C2C(=N1)N(C(=O)N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N

8-Hydroxyadenosine（Cat No.:I042661）is a modified form of the nucleoside adenosine, where a hydroxyl group is added at the 8-position of the purine ring. It is often generated as a byproduct of oxidative stress and is considered a marker of cellular damage, particularly in the context of DNA damage and repair. 8-Hydroxyadenosine has been studied for its role in various biological processes, including its potential involvement in neurodegenerative diseases, cancer, and aging. It can influence cellular signaling pathways and may provide insights into the mechanisms of oxidative damage and the cellular response to stress.