8-Methylsulfinyloctyl isothiocyanate

• CAT Number: I045563
• CAS Number: 75272-81-0
• Molecular Formula: C10H19NOS2
• Molecular Weight: 233.39
• Purity: ≥95%
• Synonyms: 1-isothiocyanato-8-methylsulfinyloctane
• InChI: InChI=1S/C10H19NOS2/c1-14(12)9-7-5-3-2-4-6-8-11-10-13/h2-9H2,1H3
• InChIKey: BCRXKWOQVFKZAG-UHFFFAOYSA-N
• SMILES: CS(=O)CCCCCCCCN=C=S

8-Methylsulfinyloctyl isothiocyanate, an isothiocyanate, has antimicrobial activity and remarkable inhibitory activity against plant growth[1]. 8-Methylsulfinyloctyl isothiocyanate impair COX-2 mediated inflammatory responses in LPS stimulated raw macrophages[2].
8-methylsulphinyloctyl isothiocyanate (1-10 μM), constituent of watercress, suppresses LPS induced production of nitric oxide and prostaglandin E2 in RAW 264.7 macrophages[2].

Reference

[1]. Jun Kawabata, et al, 8-Methylsulfinyloctyl Isothiocyanate as an Allelochemical Candidate from Rorippa sylvestris Besser, Agricultural and Biological Chemistry, Volume 53, Issue 12, 1 December 1989, Pages 3361–3362.