9-[2-(Hydroxypropyl-d6] Adenine

• CAT Number: R003475
• CAS Number: 1020719-54-3
• Molecular Formula: C₈H₅D₆N₅O
• Molecular Weight: 199.24
• Purity: ≥95%
• Synonyms: rac-Desphosphoryl Tenofovir-d6; DL-9-(2-Hydroxypropyl)adenine-d6; 6-Amino-α-(methyl-d3)-9H-purine-9-ethan-α,β,β-d3-ol
• Storage: -20°C
• IUPAC Name: (2S)-1-(6-aminopurin-9-yl)-1,1,2,3,3,3-hexadeuteriopropan-2-ol
• InChI: InChI=1S/C8H11N5O/c1-5(14)2-13-4-12-6-7(9)10-3-11-8(6)13/h3-5,14H,2H2,1H3,(H2,9,10,11)/t5-/m0/s1/i1D3,2D2,5D
• InChIKey: MJZYTEBKXLVLMY-BWBMVNDDSA-N
• SMILES: [2H][C@](C([2H])([2H])[2H])(C([2H])([2H])N1C=NC2=C(N=CN=C21)N)O

9-[2-(Hydroxypropyl-d6)] Adenine is a deuterated derivative of 9-[2-(Hydroxypropyl)] Adenine, a modified nucleobase used in biochemical and pharmacological research. The deuterium atoms facilitate precise tracking and quantification of the compound in metabolic and pharmacokinetic studies, providing insights into its behavior and interactions in biological systems. In pharmaceutical research, this labeled compound helps elucidate the metabolic pathways and mechanisms of nucleobase analogs, contributing to drug development and optimization. In organic chemistry, it aids in the study of reaction mechanisms and the synthesis of deuterium-labeled nucleobases, enhancing analytical techniques and supporting the advancement of nucleic acid research.