9,10-Dihydroergostine

• CAT Number: R041682
• CAS Number: 3609-19-6
• Molecular Formula: C34H39N5O5
• Molecular Weight: 597.716
• Purity: ≥95%
• Synonyms: (5’α,10α)-2’-Ethyl-9,10-dihydro-12’-hydroxy-5’-(phenylmethyl)-ergotaman-3’,6’,18-trione; DE 145; Dihydroergostine; Indolo[4,3-fg]quinoline, Ergotaman-3’,6’,18-trione Deriv.
• Storage: Store at RT
• IUPAC Name: (6aR,9R,10aR)-N-[(1S,2S,4R,7S)-7-benzyl-4-ethyl-2-hydroxy-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
• InChI: InChI=1S/C34H39N5O5/c1-3-33(36-30(40)22-16-24-23-11-7-12-25-29(23)21(18-35-25)17-26(24)37(2)19-22)32(42)39-27(15-20-9-5-4-6-10-20)31(41)38-14-8-13-28(38)34(39,43)44-33/h4-7,9-12,18,22,24,26-28,35,43H,3,8,13-17,19H2,1-2H3,(H,36,40)/t22-,24-,26-,27+,28+,33-,34+/m1/s1
• InChIKey: DFWHWFLWRXBPGX-UHFAATNVSA-N
• SMILES: CCC1(C(=O)N2C(C(=O)N3CCCC3C2(O1)O)CC4=CC=CC=C4)NC(=O)C5CC6C(CC7=CNC8=CC=CC6=C78)N(C5)C

9,10-Dihydroergostine (CAS 3609-19-6) is a ergot alkaloid that exhibits potential neuroprotective properties.

Reference

1.Ulrich, J., and J. Siggaard-Andersen. "Vascular effects of dihydrogenated ergot alkaloids: Comparative effects of dihydroergostine and dihydroergotamine on the blood flow and the capacitance vessels in the human calf studied by plethysmography." Angiology 22.11 (1971): 622-628.
2.Ingemann-Hansen, T., and J. Halkjaer-Kristensen. "Maximum oxygen consumption rate and dihydrogenated ergot alkaloids in humans." British journal of sports medicine 18.2 (1984): 70-73.