For research use only. Not for therapeutic Use.
A-381393(CAT: I000245) is a potent and selective agonist of the dopamine D4 receptor, a key modulator of cognitive, emotional, and behavioral processes. By selectively activating D4 receptors, it aids in understanding their role in neuropsychiatric conditions such as schizophrenia, attention-deficit hyperactivity disorder (ADHD), and mood disorders. A-381393 is particularly valuable in neuroscience research, enabling the exploration of dopaminergic signaling pathways and the development of targeted therapeutics. Its high specificity and efficacy make it an essential tool for advancing studies on D4 receptor-mediated mechanisms and potential therapeutic applications.
| Catalog Number | I000245 |
| CAS Number | 726174-00-1 |
| Synonyms | A-381393;2-[[4-(3,4-dimethylphenyl)piperazin-1-yl]methyl]-1H-benzimidazole |
| Molecular Formula | C20H24N4 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | Soluble in DMSO |
| Storage | Store at RT |
| IUPAC Name | 2-[[4-(3,4-dimethylphenyl)piperazin-1-yl]methyl]-1H-benzimidazole |
| InChI | InChI=1S/C20H24N4/c1-15-7-8-17(13-16(15)2)24-11-9-23(10-12-24)14-20-21-18-5-3-4-6-19(18)22-20/h3-8,13H,9-12,14H2,1-2H3,(H,21,22) |
| InChIKey | SAQMCVDGOIRQTC-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(N2CCN(CC3=NC4=CC=CC=C4N3)CC2)C=C1C |
