For research use only. Not for therapeutic Use.
A 438079 HCl(CAT: I005381) is a high-purity competitive antagonist targeting the P2X7 receptor, widely utilized in pharmaceutical and biomedical research. With a pIC50 of 6.9 for inhibiting Ca²⁺ influx in human recombinant P2X7 cell lines, this compound is instrumental in studies exploring the role of P2X7 in immune responses, neuroinflammation, and chronic pain. Its selective inhibition allows precise investigation into P2X7 receptor-mediated pathways, aiding the development of novel therapeutic strategies. A 438079 HCl ensures consistent and reliable results in preclinical research, offering a robust solution for exploring receptor signaling and potential drug candidates targeting inflammatory and neurological disorders.
| Catalog Number | I005381 |
| CAS Number | 899431-18-6 |
| Synonyms | 3-[[5-(2,3-dichlorophenyl)tetrazol-1-yl]methyl]pyridine;hydrochloride |
| Molecular Formula | C13H9Cl2N5 • HCl |
| Purity | ≥95% |
| Target | P2X Receptor |
| Solubility | 10 mM in DMSO |
| Storage | Store at -20°C |
| IUPAC Name | 3-[[5-(2,3-dichlorophenyl)tetrazol-1-yl]methyl]pyridine;hydrochloride |
| InChI | InChI=1S/C13H9Cl2N5.ClH/c14-11-5-1-4-10(12(11)15)13-17-18-19-20(13)8-9-3-2-6-16-7-9;/h1-7H,8H2;1H |
| InChIKey | MBTJFFMIPPMRGR-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C(=C1)Cl)Cl)C2=NN=NN2CC3=CN=CC=C3.Cl |
