For research use only. Not for therapeutic Use.
A-552 is a first-in-class potent antagonist of human IL-36γ, but not the closely related family member IL-36α.
| Catalog Number | I021105 |
| Synonyms | A-552; A 552; A552 |
| Molecular Formula | C28H27N3O4 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | (S)-2-((4-(3-Amino-4-methylphenyl)-6-methylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid |
| InChI | InChI=1S/C28H27N3O4/c1-18-14-15-20(17-23(18)29)24-16-19(2)30-27(31-24)35-25(26(32)33)28(34-3,21-10-6-4-7-11-21)22-12-8-5-9-13-22/h4-17,25H,29H2,1-3H3,(H,32,33)/t25-/m1/s1 |
| InChIKey | GDPBXJYDHBGQBK-RUZDIDTESA-N |
| SMILES | O=C(O)[C@@H](OC1=NC(C)=CC(C2=CC=C(C)C(N)=C2)=N1)C(C3=CC=CC=C3)(OC)C4=CC=CC=C4 |
