A23187, 4-Bromo

• CAT Number: R000109
• CAS Number: 76455-48-6
• Molecular Formula: C29H36BrN3O6
• Molecular Weight: 602.53
• Purity: ≥95%
• Synonyms: 4-Bromocalcimycin;4-bromo-Calcium Ionophore A-23187
• Target: Neuronal Signaling
• Storage: 2°C to 8°C
• IUPAC Name: 6-bromo-5-(methylamino)-2-[[(2S,3R,5R,6S,8R,9R)-3,5,9-trimethyl-2-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylic acid
• InChI: InChI=1S/C29H36BrN3O6/c1-14-8-9-29(16(3)11-15(2)27(39-29)17(4)26(34)19-7-6-10-32-19)38-20(14)13-22-33-25-21(37-22)12-18(30)24(31-5)23(25)28(35)36/h6-7,10,12,14-17,20,27,31-32H,8-9,11,13H2,1-5H3,(H,35,36)/t14-,15-,16-,17-,20-,27+,29+/m1/s1
• InChIKey: LDXQFZZGVTWFCF-FHYGWRBKSA-N
• SMILES: CC1CCC2(C(CC(C(O2)C(C)C(=O)C3=CC=CN3)C)C)OC1CC4=NC5=C(C(=C(C=C5O4)Br)NC)C(=O)O

A23187, 4-Bromo is a calcium ionophore derivative widely used in research to facilitate the transport of divalent cations, such as Ca²⁺ and Mg²⁺, across biological membranes. By increasing intracellular calcium levels, it plays a critical role in studying calcium-dependent processes, including signal transduction, enzyme activation, and apoptosis. Its specificity and potency make it a valuable tool for investigating cellular functions, particularly in immunology and cell biology, where calcium signaling is a key regulator of physiological and pathological processes.