For research use only. Not for therapeutic Use.
A286982(CAT: I000187) is a small molecule inhibitor that targets the interaction between LFA-1 and ICAM-1, which are important proteins involved in cell adhesion and migration. By inhibiting this interaction, A286982 has potential therapeutic applications in the treatment of inflammatory and autoimmune diseases, as well as in preventing organ rejection after transplantation.
| Catalog Number | I000187 |
| CAS Number | 280749-17-9 |
| Synonyms | A286982;(E)-1-(4-acetylpiperazin-1-yl)-3-[3-nitro-4-(2-propan-2-ylphenyl)sulfanylphenyl]prop-2-en-1-one |
| Molecular Formula | C24H27N3O4S |
| Purity | ≥95% |
| Target | Integrin |
| Solubility | Soluble in DMSO |
| Storage | Store at RT |
| IUPAC Name | (E)-1-(4-acetylpiperazin-1-yl)-3-[3-nitro-4-(2-propan-2-ylphenyl)sulfanylphenyl]prop-2-en-1-one |
| InChI | InChI=1S/C24H27N3O4S/c1-17(2)20-6-4-5-7-22(20)32-23-10-8-19(16-21(23)27(30)31)9-11-24(29)26-14-12-25(13-15-26)18(3)28/h4-11,16-17H,12-15H2,1-3H3/b11-9+ |
| InChIKey | HTGGAYLWTDOFDK-PKNBQFBNSA-N |
| SMILES | CC(C)C1=CC=CC=C1SC2=C(C=C(C=C2)C=CC(=O)N3CCN(CC3)C(=O)C)[N+](=O)[O-] |
