For research use only. Not for therapeutic Use.
A2ti-1（Cat No.:I015192）is a potent, selective inhibitor of the adenosine A2A receptor, which plays a key role in regulating immune response and inflammatory pathways. This compound has shown promise in modulating immune cell function and reducing inflammation, making it a potential therapeutic candidate for diseases such as autoimmune disorders, cancer, and neurodegenerative diseases. A2ti-1 has been used in experimental settings to explore the modulation of the adenosine pathway and its effects on immune responses, highlighting its potential as a targeted therapeutic agent.
| Catalog Number | I015192 |
| CAS Number | 570390-00-0 |
| Molecular Formula | C₂₀H₂₂N₄O₂S |
| Purity | ≥95% |
| Target | Virus Protease |
| IUPAC Name | 2-[[4-(2-ethylphenyl)-5-[(2-methylphenoxy)methyl]-1,2,4-triazol-3-yl]sulfanyl]acetamide |
| InChI | InChI=1S/C20H22N4O2S/c1-3-15-9-5-6-10-16(15)24-19(22-23-20(24)27-13-18(21)25)12-26-17-11-7-4-8-14(17)2/h4-11H,3,12-13H2,1-2H3,(H2,21,25) |
| InChIKey | KNQGIFUBCFRGDB-UHFFFAOYSA-N |
| SMILES | CCC1=CC=CC=C1N2C(=NN=C2SCC(=O)N)COC3=CC=CC=C3C |
| Reference | [1]. Tummala R K Reddy, et al.Three-dimensional Pharmacophore Design and Biochemical Screening Identifies Substituted 1,2,4-triazoles as Inhibitors of the Annexin A2-S100A10 Protein Interaction. ChemMedChem. 2012 Aug;7(8):1435-46.<br>[2]. Andrew W Woodham, et al. Small Molecule Inhibitors of the Annexin A2 Heterotetramer Prevent Human Papillomavirus Type 16 Infection. J Antimicrob Chemother. 2015;70(6):1686-90. |
