AA-CW236

For research use only. Not for therapeutic Use.

  • CAT Number: I021173
  • CAS Number: 1869921-96-9
  • Molecular Formula: C17H16ClF3N4O2
  • Molecular Weight: 400.78
  • Purity: ≥95%
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AA-CW236 is a MGMT (O6-methylguanine DNA methyltransferase) inhibitor. AA-CW236 targets MGMT active site Cys145 for covalent modification[1].


Catalog Number I021173
CAS Number 1869921-96-9
Synonyms

4-[2-[5-(chloromethyl)-4-[4-(trifluoromethoxy)phenyl]triazol-1-yl]ethyl]-3,5-dimethyl-1,2-oxazole

Molecular Formula C17H16ClF3N4O2
Purity ≥95%
InChI InChI=1S/C17H16ClF3N4O2/c1-10-14(11(2)27-23-10)7-8-25-15(9-18)16(22-24-25)12-3-5-13(6-4-12)26-17(19,20)21/h3-6H,7-9H2,1-2H3
InChIKey MPDMMSRZEHOFPA-UHFFFAOYSA-N
SMILES CC1=C(C(=NO1)C)CCN2C(=C(N=N2)C3=CC=C(C=C3)OC(F)(F)F)CCl
Reference

[1]. AA-CW236 is a MGMT (O6-methylguanine DNA methyltransferase) inhibitor. AA-CW236 targets MGMT active site Cys145 for covalent modification.
 [Content Brief]

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