For research use only. Not for therapeutic Use.
AA74-1 is a potent and selective inhibitor of APEH. AA74-1 significantly increases T cells proliferation by blocking the APEH activity[1].
| CAS Number | 1361532-00-4 |
| Synonyms | [4-(4-hydroxy-2,6-dimethylheptan-4-yl)triazol-2-yl]-pyrrolidin-1-ylmethanone |
| Molecular Formula | C16H28N4O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C16H28N4O2/c1-12(2)9-16(22,10-13(3)4)14-11-17-20(18-14)15(21)19-7-5-6-8-19/h11-13,22H,5-10H2,1-4H3 |
| InChIKey | GXBVPGCIMCIASQ-UHFFFAOYSA-N |
| SMILES | CC(C)CC(CC(C)C)(C1=NN(N=C1)C(=O)N2CCCC2)O |
| Reference | [1]. Adibekian A, et al. Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors. Nat Chem Biol. 2011 May 15;7(7):469-78. |
