For research use only. Not for therapeutic Use.
Abacavir hydroxyacetate（Cat No.:I000529）is a modified form of abacavir, an antiretroviral drug commonly used in the treatment of HIV infection. The hydroxyacetate modification aims to enhance the drug’s pharmacokinetics, bioavailability, or stability. Abacavir works by inhibiting the reverse transcriptase enzyme, preventing the replication of the HIV virus. The hydroxyacetate ester may improve its solubility, making it more effective in certain formulations or for specific patient populations. This modification is designed to optimize the delivery and efficacy of abacavir, offering a potential advancement in HIV therapy and treatment regimens.
| CAS Number | 1446418-48-9 |
| Synonyms | [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl 2-hydroxyacetate |
| Molecular Formula | C16H20N6O3 |
| Purity | ≥95% |
| IUPAC Name | [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl 2-hydroxyacetate |
| InChI | InChI=1S/C16H20N6O3/c17-16-20-14(19-10-2-3-10)13-15(21-16)22(8-18-13)11-4-1-9(5-11)7-25-12(24)6-23/h1,4,8-11,23H,2-3,5-7H2,(H3,17,19,20,21)/t9-,11+/m1/s1 |
| InChIKey | ZBBZROWQLKCFQK-KOLCDFICSA-N |
| SMILES | C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)COC(=O)CO |
