Abacavir sulfate

• CAT Number: A001048
• CAS Number: 188062-50-2
• Molecular Formula: C14H18N6O.1/2 H2O4S
• Molecular Weight: 335.35
• Purity: ≥95%
• Synonyms: 1592U89
• Target: HIV-1 reverse-transcriptase
• Storage: 3 years -20C powder
• IUPAC Name: [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol;sulfuric acid
• InChI: InChI=1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1
• InChIKey: WMHSRBZIJNQHKT-FFKFEZPRSA-N
• SMILES: C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)CO.C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)CO.OS(=O)(=O)O

Abacavir Sulfate（Cat No.:A001048）is a high-purity nucleoside reverse transcriptase inhibitor (NRTI) widely used in HIV research. It inhibits HIV-1 reverse transcriptase, preventing viral DNA synthesis and disrupting replication. The sulfate form enhances its solubility and stability, making it ideal for experimental and pharmacological studies. Abacavir Sulfate is a crucial tool for investigating mechanisms of antiretroviral activity, resistance, and combination therapies. Its efficacy and specificity make it essential for advancing research into innovative treatments aimed at managing HIV infections and improving outcomes in antiretroviral therapy.