Abacavir sulfate

• CAT Number: I013894
• CAS Number: 188062-50-2
• Molecular Formula: C₁₄H₁₈N₆O
• Molecular Weight: 286.33
• Purity: ≥95%
• Target: Cell Cycle/DNA Damage
• Solubility: 10 mM in H2O
• IUPAC Name: [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol;sulfuric acid
• InChI: InChI=1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1
• InChIKey: WMHSRBZIJNQHKT-FFKFEZPRSA-N
• SMILES: C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)CO.C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)CO.OS(=O)(=O)O

Abacavir sulfate（Cat No.:I013894）is a nucleoside reverse transcriptase inhibitor (NRTI) widely used in HIV research and antiretroviral therapy. It works by inhibiting the reverse transcriptase enzyme, preventing the conversion of viral RNA into DNA, thereby halting viral replication. Abacavir sulfate is instrumental in studying resistance mechanisms, pharmacokinetics, and optimizing combination therapies for HIV management. Its high efficacy and well-established role in antiretroviral regimens make it a cornerstone in HIV research, contributing to the development of effective treatments and improving outcomes for patients with HIV infection.