For research use only. Not for therapeutic Use.
Abacavir Sulfate(Cat No.:M128746)is a high-purity nucleoside reverse transcriptase inhibitor (NRTI) widely used in HIV research. It targets HIV-1 reverse transcriptase, disrupting viral replication by causing premature termination of the growing DNA chain. The sulfate form enhances its solubility and stability, making it suitable for various experimental setups. Abacavir Sulfate is pivotal in studying antiretroviral mechanisms, resistance development, and combination therapy strategies. Its efficacy and specificity make it an essential compound in advancing HIV drug discovery and therapeutic development aimed at managing and treating HIV infections.
Catalog Number | M128746 |
CAS Number | 136777-48-5 |
Molecular Formula | C28H38N12O6S |
Purity | ≥95% |
Target | Apoptosis |
Storage | -80°C |
IUPAC Name | [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol;sulfuric acid |
InChI | InChI=1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1 |
InChIKey | WMHSRBZIJNQHKT-FFKFEZPRSA-N |
SMILES | C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)CO.C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)CO.OS(=O)(=O)O |