Abietic Acid

• CAT Number: R057001
• CAS Number: 514-10-3
• Molecular Formula: C20H30O2
• Molecular Weight: 302.45
• Purity: ≥95%
• Synonyms: (1R,4aR,4bR,10aR)-1,2,3,4,4a,4b,5,6,10,10a-Decahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxylic Acid; 13-Isopropylpodocarpa-7,13-dien-15-oic Acid; (-)-Abietic Acid; 7,13-Abietadien-18-oic Acid; Abietic Acid; NSC 25149; Odomit B 10; Sylv
• Target: Bacterial
• Storage: -20°C
• IUPAC Name: (1R,4aR,4bR,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,4b,5,6,10,10a-octahydrophenanthrene-1-carboxylic acid
• InChI: InChI=1S/C20H30O2/c1-13(2)14-6-8-16-15(12-14)7-9-17-19(16,3)10-5-11-20(17,4)18(21)22/h7,12-13,16-17H,5-6,8-11H2,1-4H3,(H,21,22)/t16-,17+,19+,20+/m0/s1
• InChIKey: RSWGJHLUYNHPMX-ONCXSQPRSA-N
• SMILES: CC(C)C1=CC2=CC[C@@H]3[C@@]([C@H]2CC1)(CCC[C@@]3(C)C(=O)O)C

Abietic Acid（Cat No.:R057001）is a natural resin acid primarily derived from pine trees, widely used in industrial applications such as adhesives, varnishes, and inks due to its binding and film-forming properties. Known for its antimicrobial and anti-inflammatory effects, abietic acid is also studied in pharmacology for potential applications in treating inflammation and bacterial infections. Its chemical stability and versatility make it valuable in formulations requiring a natural resin component. In its refined form, abietic acid is additionally utilized as a raw material in producing ester gums and other resin derivatives.

Reference

1.Liu, Xiaoqing, Wenbo Xin, and Jinwen Zhang. "Rosin-derived imide-diacids as epoxy curing agents for enhanced performance." Bioresource technology 101.7 (2010): 2520-2524.
2.Liu, Xiaoqing, Wenbo Xin, and Jinwen Zhang. "Rosin-based acid anhydrides as alternatives to petrochemical curing agents." Green Chemistry 11.7 (2009): 1018-1025.
3.Gigante, Bárbara, et al. "Structural effects on the bioactivity of dehydroabietic acid derivatives." Planta medica 68.08 (2002): 680-684.
4.Zapata, Bibiana, et al. "Cytotoxic, immunomodulatory, antimycotic, and antiviral activities of semisynthetic 14-hydroxyabietane derivatives and triptoquinone C-4 epimers." MedChemComm 4.9 (2013): 1239-1246.
5.Alvarez-Manzaneda, Enrique, et al. "Regioselective routes towards 14-hydroxyabietane diterpenes. A formal synthesis of immunosuppressant (−)-triptolide from (+)-abietic acid." Tetrahedron 63.45 (2007): 11204-11212.