For research use only. Not for therapeutic Use.
ABT-224, also known as Ampalex, is a 5-HT4 agonists potentially for the treatment of constipation.
| Catalog Number | I000759 |
| CAS Number | 287399-47-7 |
| Synonyms | ABT-224; AU-224; ABT224; AU224; ABT 224; AU 224;piperidin-1-yl(quinoxalin-6-yl)methanone |
| Molecular Formula | C14H15N3O |
| Purity | ≥95% |
| Target | 5-HT4 agonist |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4°Cfor short term (days to weeks), or -20 °C for long term (months). |
| InChI | InChI=1S/C14H15N3O/c18-14(17-8-2-1-3-9-17)11-4-5-12-13(10-11)16-7-6-15-12/h4-7,10H,1-3,8-9H2 |
| InChIKey | ANDGGVOPIJEHOF-UHFFFAOYSA-N |
| SMILES | O=C(N1CCCCC1)C2=CC=C3N=CC=NC3=C2 |
| Reference | </br>1: Knapp RJ, Goldenberg R, Shuck C, Cecil A, Watkins J, Miller C, Crites G, Malatynska E. Antidepressant activity of memory-enhancing drugs in the reduction of submissive behavior model. Eur J Pharmacol. 2002 Apr 5;440(1):27-35. PubMed PMID: 11959085.</br></br> |
