ABT 737-d8

• CAT Number: R012098
• CAS Number: 1217686-68-4
• Molecular Formula: C42H45ClN6O5S2
• Molecular Weight: 821.478
• Purity: ≥95%
• Synonyms: 4-[4-[(4’-Chloro[1,1’-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide-d8
• Storage: -20°C
• IUPAC Name: 4-[4-[[2-(4-chlorophenyl)phenyl]methyl]-2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl]-N-[4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylbenzamide
• InChI: InChI=1S/C42H45ClN6O5S2/c1-46(2)23-22-35(30-55-37-9-4-3-5-10-37)44-40-21-20-38(28-41(40)49(51)52)56(53,54)45-42(50)32-14-18-36(19-15-32)48-26-24-47(25-27-48)29-33-8-6-7-11-39(33)31-12-16-34(43)17-13-31/h3-21,28,35,44H,22-27,29-30H2,1-2H3,(H,45,50)/t35-/m1/s1/i24D2,25D2,26D2,27D2
• InChIKey: HPLNQCPCUACXLM-GDWIFBKKSA-N
• SMILES: CN(C)CCC(CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCN(CC4)CC5=CC=CC=C5C6=CC=C(C=C6)Cl)[N+](=O)[O-]

ABT 737-d8 is a deuterated analog of the BH3 mimetic ABT 737, featuring eight deuterium atoms for enhanced stability and precision in research. This isotopically labeled compound is essential for studying the pharmacokinetics, metabolism, and anti-cancer effects of ABT 737 in apoptotic pathway research. ABT 737-d8 ensures reliable and consistent results in advanced pharmaceutical research and clinical studies, making it a valuable tool for scientists and healthcare professionals developing new cancer therapies. Ideal for use in mass spectrometry and other analytical techniques, it supports accurate tracking in biological systems.