For research use only. Not for therapeutic Use.
AC-261066 is a potent, orally available and isoform-selective retinoic acid beta2 (RARbeta2) receptor agonist, with a pEC50 of 8.0[1].
AC-261066 exhibits good oral bioavailability in rats (F oral = 52%)[1].
| Catalog Number | I000996 |
| CAS Number | 870773-76-5 |
| Synonyms | 4-[4-(2-butoxyethoxy)-5-methyl-1,3-thiazol-2-yl]-2-fluorobenzoic acid |
| Molecular Formula | C17H20FNO4S |
| Purity | ≥95% |
| InChI | InChI=1S/C17H20FNO4S/c1-3-4-7-22-8-9-23-15-11(2)24-16(19-15)12-5-6-13(17(20)21)14(18)10-12/h5-6,10H,3-4,7-9H2,1-2H3,(H,20,21) |
| InChIKey | HSAOETBFVAWNRP-UHFFFAOYSA-N |
| SMILES | CCCCOCCOC1=C(SC(=N1)C2=CC(=C(C=C2)C(=O)O)F)C |
| Reference | [1]. Lund BW, et al. Discovery of a potent, orally available, and isoform-selective retinoic acid beta2 receptor agonist. J Med Chem. 2005 Dec 1;48(24):7517-9. |
