AC-DEVD-CHO

• CAT Number: M044295
• CAS Number: 184179-08-6
• Molecular Formula: C20H30N4O11
• Molecular Weight: 502.48
• Purity: ≥95%
• Synonyms: N-Ac-Asp-Glu-Val-Asp-CHO
• Storage: -20°C
• IUPAC Name: (4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-1-carboxy-3-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid
• InChI: InChI=1S/C20H30N4O11/c1-9(2)17(20(35)22-11(8-25)6-15(29)30)24-18(33)12(4-5-14(27)28)23-19(34)13(7-16(31)32)21-10(3)26/h8-9,11-13,17H,4-7H2,1-3H3,(H,21,26)(H,22,35)(H,23,34)(H,24,33)(H,27,28)(H,29,30)(H,31,32)/t11-,12-,13-,17-/m0/s1
• InChIKey: UMBVAPCONCILTL-MRHIQRDNSA-N
• SMILES: CC(C)C(C(=O)NC(CC(=O)O)C=O)NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C

AC-DEVD-CHO（Cat No.:M044295）is a potent, cell-permeable, and reversible inhibitor of caspase-3, a crucial enzyme in the apoptosis pathway. This aldehyde peptide inhibitor, with the sequence acetyl-Asp-Glu-Val-Asp-CHO, mimics the natural substrate of caspase-3, binding to its active site to prevent enzymatic activity. AC-DEVD-CHO is widely used in research to study apoptosis mechanisms, evaluate the role of caspase-3 in various diseases, and develop potential therapeutic strategies targeting cell death processes. Its high specificity and effectiveness make it a valuable tool for apoptosis and cell signaling studies.