Ac-DEVD-CHO

• CAT Number: M134470
• CAS Number: 169332-60-9
• Molecular Formula: C₂₀H₃₀N₄O₁₁
• Molecular Weight: 502.48
• Purity: ≥95%
• Target: Caspase
• Storage: -20°C
• IUPAC Name: (4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-1-carboxy-3-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid
• InChI: InChI=1S/C20H30N4O11/c1-9(2)17(20(35)22-11(8-25)6-15(29)30)24-18(33)12(4-5-14(27)28)23-19(34)13(7-16(31)32)21-10(3)26/h8-9,11-13,17H,4-7H2,1-3H3,(H,21,26)(H,22,35)(H,23,34)(H,24,33)(H,27,28)(H,29,30)(H,31,32)/t11-,12-,13-,17-/m0/s1
• InChIKey: UMBVAPCONCILTL-MRHIQRDNSA-N
• SMILES: CC(C)[C@@H](C(=O)N[C@@H](CC(=O)O)C=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)C

Ac-DEVD-CHO(Cat No.:M134470) is a chemical compound used in biological research and pharmaceutical studies. Its mode of action involves being a specific inhibitor of caspases, a group of protease enzymes involved in apoptosis (programmed cell death). Ac-DEVD-CHO is designed to selectively block caspase-3 activity, which plays a crucial role in apoptotic cell death. Researchers use it as a tool to investigate the mechanisms of apoptosis and to study the role of caspases in various cellular processes. Additionally, Ac-DEVD-CHO finds applications in drug development, particularly in the design and testing of potential caspase inhibitors for therapeutic purposes.