For research use only. Not for therapeutic Use.
Ac-Lys-AMC (Hexanamide), also termed MAL, is a fluorescent substrate for histone deacetylase HDACs[1].
Catalog Number | M104492 |
CAS Number | 156661-42-6 |
Synonyms | (2S)-2-acetamido-6-amino-N-(4-methyl-2-oxochromen-7-yl)hexanamide |
Molecular Formula | C18H23N3O4 |
Purity | ≥95% |
InChI | InChI=1S/C18H23N3O4/c1-11-9-17(23)25-16-10-13(6-7-14(11)16)21-18(24)15(20-12(2)22)5-3-4-8-19/h6-7,9-10,15H,3-5,8,19H2,1-2H3,(H,20,22)(H,21,24)/t15-/m0/s1 |
InChIKey | NBOQAQRQQNJREL-HNNXBMFYSA-N |
SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCCN)NC(=O)C |
Reference | [1]. Heltweg B, et al. Nonisotopic substrate for assaying both human zinc and NAD+-dependent histone deacetylases. Anal Biochem. 2003 Aug 1;319(1):42-8. |