Acebutolol

• CAT Number: I001075
• CAS Number: 37517-30-9
• Molecular Formula: C18H28N2O4
• Molecular Weight: 336.43
• Purity: ≥95%
• Synonyms: Acebutolol; Acetobutolol; Neptal; Prent; Sectral; Dl-Acebutolol.;N-[3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanamide
• Target: Neuronal Signaling
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4°Cfor short term (days to weeks), or -20 °C for long term (months).
• IUPAC Name: N-[3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanamide
• InChI: InChI=1S/C18H28N2O4/c1-5-6-18(23)20-14-7-8-17(16(9-14)13(4)21)24-11-15(22)10-19-12(2)3/h7-9,12,15,19,22H,5-6,10-11H2,1-4H3,(H,20,23)
• InChIKey: GOEMGAFJFRBGGG-UHFFFAOYSA-N
• SMILES: CCCC(=O)NC1=CC(=C(C=C1)OCC(CNC(C)C)O)C(=O)C

Acebutolol（Cat No.:I001075）is a selective beta-1 adrenergic antagonist (beta-blocker) used primarily to treat hypertension and certain cardiac arrhythmias. By blocking beta-1 receptors in the heart, Acebutolol reduces heart rate, myocardial contractility, and blood pressure, making it effective in managing conditions like high blood pressure, angina, and arrhythmias. It also has mild intrinsic sympathomimetic activity, meaning it can partially stimulate beta-1 receptors while blocking excessive stimulation. This characteristic may help maintain heart rate in some patients. Acebutolol is well-tolerated but may have side effects, including dizziness and fatigue, which require careful monitoring during treatment.