Acetaminophen Glutathione-d3 Disodium Salt

• CAT Number: R057478
• CAS Number: NA
• Molecular Formula: C₁₈H₁₉D₃N₄Na₂O₈S
• Molecular Weight: 503.45
• Purity: ≥95%
• Synonyms: L-γ-Glutamyl-S-[5-(acetylamino)-2-hydroxyphenyl]-L-cysteinylglycine Disodium Salt-d3; 3-(Glutathion-S-yl)acetaminophen Disodium Salt-d3; 3-Glutathionylacetaminophen Disodium-d3; Acetaminophen-glutathione Adduct Disodium-d3
• Storage: -20°C
• IUPAC Name: disodium;(2S)-2-amino-5-[[(2R)-1-(carboxylatomethylamino)-3-[2-hydroxy-5-[(2,2,2-trideuterioacetyl)amino]phenyl]sulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoate
• InChI: InChI=1S/C18H24N4O8S.2Na/c1-9(23)21-10-2-4-13(24)14(6-10)31-8-12(17(28)20-7-16(26)27)22-15(25)5-3-11(19)18(29)30;;/h2,4,6,11-12,24H,3,5,7-8,19H2,1H3,(H,20,28)(H,21,23)(H,22,25)(H,26,27)(H,29,30);;/q;2*+1/p-2/t11-,12-;;/m0../s1/i1D3
• InChIKey: PFUAJERIABFVCS-HCEPZJLESA-L
• SMILES: CC(=O)NC1=CC(=C(C=C1)O)SCC(C(=O)NCC(=O)[O-])NC(=O)CCC(C(=O)[O-])N.[Na+].[Na+]

Acetaminophen Glutathione-d3 Disodium Salt（Cat No.:R057478） is a deuterated form of a conjugate compound where three hydrogen atoms in the glutathione moiety are replaced with deuterium. This isotopic labeling enhances the stability and traceability of the molecule, crucial for studying the detoxification pathways of acetaminophen. The compound forms as part of the metabolic process when acetaminophen is broken down in the liver, involving conjugation with glutathione. Its deuterated version provides precise insights into this biochemical interaction, aiding in understanding and monitoring potential hepatotoxicity caused by acetaminophen overdose and its safe usage in medical treatments.