Acetyl-CoA Carboxylase-IN-1

• CAT Number: R027601
• CAS Number: 179343-23-8
• Molecular Formula: C13H9Br2N5
• Molecular Weight: 395.05
• Purity: ≥95%
• Synonyms: 6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine
• InChI: InChI=1S/C13H9Br2N5/c14-8-2-1-3-9(15)10(8)7-4-6-5-18-13(17)20-12(6)19-11(7)16/h1-5H,(H4,16,17,18,19,20)
• InChIKey: HGIPWJYTPOHUGK-UHFFFAOYSA-N
• SMILES: C1=CC(=C(C(=C1)Br)C2=C(N=C3C(=C2)C=NC(=N3)N)N)Br

Acetyl-CoA Carboxylase-IN-1（Cat No.:R027601）is a small molecule inhibitor targeting acetyl-CoA carboxylase (ACC), an enzyme crucial for fatty acid synthesis and metabolism. ACC catalyzes the conversion of acetyl-CoA to malonyl-CoA, a key step in lipid biosynthesis. By inhibiting ACC, Acetyl-CoA Carboxylase-IN-1 aims to disrupt lipid metabolism, which is implicated in various metabolic disorders and cancers. The inhibition of ACC may reduce the accumulation of fatty acids in cells, potentially slowing tumor growth and improving outcomes in diseases like obesity, diabetes, and cardiovascular diseases. Preclinical studies show promise for its therapeutic potential.