AChE-IN-23

• CAT Number: I043002
• CAS Number: 6297-14-9
• Molecular Formula: C11H20Cl2N2O
• Molecular Weight: 267.20
• Purity: ≥95%
• Synonyms: 4-amino-2-(diethylaminomethyl)phenol;dihydrochloride
• InChI: InChI=1S/C11H18N2O.2ClH/c1-3-13(4-2)8-9-7-10(12)5-6-11(9)14;;/h5-7,14H,3-4,8,12H2,1-2H3;2*1H
• InChIKey: PLISWDVQSUTGTR-UHFFFAOYSA-N
• SMILES: CCN(CC)CC1=C(C=CC(=C1)N)O.Cl.Cl

AChE-IN-23 (compound 3h) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 48.3 μM[1].

Reference

[1]. Martijn Constantijn de Koning, et al. Discovery of a potent non-oxime reactivator of nerve agent inhibited human acetylcholinesterase. Eur J Med Chem. 2018 Sep 5;157:151-160.
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