Acid-PEG3-C2-Boc

• CAT Number: I016971
• CAS Number: 1807539-06-5
• Molecular Formula: C₁₄H₂₆O₇
• Molecular Weight: 306.35
• Purity: ≥95%
• Target: PROTAC Linkers

Acid-PEG3-C2-Boc (CAT: I016971) is a compound that consists of a polyethylene glycol (PEG) spacer attached to a C2 alkyl chain terminated with a Boc (tert-butoxycarbonyl) protecting group on the carboxylic acid moiety. It is commonly used as a building block in organic synthesis and drug development. The PEG spacer provides hydrophilicity and flexibility, while the C2 alkyl chain can serve as a linker or handle for further chemical modifications. The Boc protecting group can be removed under appropriate conditions to expose the free carboxylic acid for subsequent reactions.

Reference

[1]. Nathanael Gray, et al. Bifunctional molecules for degradation of egfr and methods of use. WO2017185036A1.[2]. Christopher Semko, et al. Rapamycin analogs as mtor inhibitors. WO 2018204416 A1.