For research use only. Not for therapeutic Use.
Phloxine B is a red dye, the USP grade of which is used as a color additive for food, drugs, and cosmetics. It has also been used as an alternative to Gram staining, to differentiate between Gram-negative and Gram-positive bacteria. At 100 µg/ml, it can inhibit methicillin-resistant <em>S. aureus</em> growth <em>in vitro</em>. Phloxine B has also been shown to modulate channel activity of wild-type cystic fibrosis transmembrane conductance regulator chloride channels (CFTR; K<sub>i</sub> = 38 µM) and mutant delta F508 CFTR (K<sub>i</sub> = 33 µM).
Catalog Number | M075227 |
CAS Number | 18472-87-2 |
Synonyms | Acid Red 92;Cyanosine;D&C; Red No. 28 |
Molecular Formula | C20H2Br4Cl4O5 • 2Na |
Purity | ≥95% |
Storage | -20°C |
InChIKey | OOYIOIOOWUGAHD-UHFFFAOYSA-L |