For research use only. Not for therapeutic Use.
Acloproxalap is a quinoline-based aldehyde scavenger that can be used in studies of diseases with toxic aldehyde accumulation, such as inflammatory diseases of the eye and skin, respiratory diseases such as pneumonia, organ diseases, and viral infection-related syndromes[1][2].
Acloproxalap (compound I-6) (100 or 200 mg/kg, i.p. or p.o., everyday, 6 days) can effectively improve inflammation of the colon in acute ulcerative colitis (UC) female Swiss Webster mice[1].
| Catalog Number | I043423 |
| CAS Number | 1824609-67-7 |
| Synonyms | 2-(3-aminoquinolin-2-yl)propan-2-ol |
| Molecular Formula | C12H14N2O |
| Purity | ≥95% |
| InChI | InChI=1S/C12H14N2O/c1-12(2,15)11-9(13)7-8-5-3-4-6-10(8)14-11/h3-7,15H,13H2,1-2H3 |
| InChIKey | NOFRQDXKZDAYGB-UHFFFAOYSA-N |
| SMILES | CC(C)(C1=NC2=CC=CC=C2C=C1N)O |
| Reference | [1]. Susan Macdonald, et al. Treatment of inflammatory disorders. US20190105322 [2]. Todd Brady, et al. Pharmaceutical formulations and uses thereof. WO2021231792 |
