Acotiamide hydrochloride trihydrate

• CAT Number: I000491
• CAS Number: 773092-05-0 (HCl hydrate)
• Molecular Formula: C21H37ClN4O8S
• Molecular Weight: 541.06
• Purity: ≥95%
• Target: Cholinesterase (ChE)
• Solubility: Soluble in DMSO.
• Storage: 0 - 4°Cfor short term (days to weeks), or -20 °C for long term (months).
• IUPAC Name: N-[2-[di(propan-2-yl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-1,3-thiazole-4-carboxamide;trihydrate;hydrochloride
• InChI: InChI=1S/C21H30N4O5S.ClH.3H2O/c1-12(2)25(13(3)4)8-7-22-20(28)15-11-31-21(23-15)24-19(27)14-9-17(29-5)18(30-6)10-16(14)26;;;;/h9-13,26H,7-8H2,1-6H3,(H,22,28)(H,23,24,27);1H;3*1H2
• InChIKey: NPTDXIXCQCFGKC-UHFFFAOYSA-N
• SMILES: CC(C)N(CCNC(=O)C1=CSC(=N1)NC(=O)C2=CC(=C(C=C2O)OC)OC)C(C)C.O.O.O.Cl

Acotiamide hydrochloride trihydrate（Cat No.:I000491）is a drug used primarily in the treatment of functional dyspepsia, a condition characterized by discomfort or pain in the upper abdomen. It acts as a selective acetylcholinesterase inhibitor, which enhances cholinergic neurotransmission, improving gastric motility and reducing symptoms such as bloating, nausea, and early satiety. By increasing acetylcholine levels, acotiamide promotes the movement of food through the stomach and intestines. It also has a mild anti-inflammatory effect. Acotiamide hydrochloride trihydrate is well-tolerated in most patients, but like all medications, it requires careful monitoring for potential side effects.

Reference

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