For research use only. Not for therapeutic Use.
ACT001(DMAMCL, dimethylaminomicheliolide) is a PAI-1 inhibitor and exerts antitumor effects on neuroblastoma (NB) both in vitro and in vivo. It also exerts synergistic effects in combination with cisplatin through the inhibition of the PAI-1/PI3K/AKT pathway.
Catalog Number | I047003 |
CAS Number | 1403357-81-2 |
Molecular Formula | C17H27NO3 |
Purity | ≥95% |
Reference | [1] Xi X, et al. Cell Death Dis. 2019 Oct 7;10(10):757. |