For research use only. Not for therapeutic Use.
Actein（Cat No.:R020881）is a triterpene glycoside derived from the roots of Actaea racemosa (black cohosh), traditionally used for its medicinal properties. Actein has been studied for its potential therapeutic effects, particularly in hormone-related conditions such as menopausal symptoms. It also exhibits anti-inflammatory, antioxidant, and anticancer activities, making it of interest in pharmaceutical research. Actein has shown promise in preclinical studies for inhibiting cancer cell growth, particularly in breast cancer, by inducing apoptosis and cell cycle arrest. Its diverse bioactivity makes it a valuable natural compound for further investigation.
| Catalog Number | R020881 |
| CAS Number | 18642-44-9 |
| Synonyms | (3β,12β,16β,23R,24R,25S,26S)-12-(acetyloxy)-16,23:23,26:24,25-triepoxy-26-hydroxy-9,19-cyclolanostan-3-yl β-D-Xylopyranoside; 9,19-Cyclolanostane β-D-xylopyranoside deriv; Spiro[5H-cyclopropa[1’,8’a]naphth[2’,1’:4,5]indeno[2,1-b]pyran-10(2H),2’-[3,6] |
| Molecular Formula | C₃₈H₅₈O₁₀ |
| Purity | ≥95% |
| Target | PI3K/Akt/mTOR |
| Storage | -20°C |
| IUPAC Name | [(1S,1'R,2S,3'R,4R,4'R,5R,5'R,6'R,10'S,12'S,13'S,16'R,18'S,21'R)-2-hydroxy-1,4',6',12',17',17'-hexamethyl-18'-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyspiro[3,6-dioxabicyclo[3.1.0]hexane-4,8'-9-oxahexacyclo[11.9.0.01,21.04,12.05,10.016,21]docosane]-3'-yl] acetate |
| InChI | InChI=1S/C37H56O11/c1-17-12-37(29-34(7,47-29)30(42)48-37)46-20-13-32(5)22-9-8-21-31(3,4)23(45-28-27(41)26(40)19(39)15-43-28)10-11-35(21)16-36(22,35)14-24(44-18(2)38)33(32,6)25(17)20/h17,19-30,39-42H,8-16H2,1-7H3/t17-,19-,20+,21+,22+,23+,24-,25+,26+,27-,28+,29-,30+,32+,33-,34+,35-,36+,37-/m1/s1 |
| InChIKey | NEWMWGLPJQHSSQ-PSDKAYTQSA-N |
| SMILES | C[C@@H]1C[C@@]2([C@H]3[C@](O3)([C@H](O2)O)C)O[C@@H]4[C@H]1[C@]5([C@@H](C[C@@]67C[C@@]68CC[C@@H](C([C@@H]8CC[C@H]7[C@@]5(C4)C)(C)C)O[C@H]9[C@@H]([C@H]([C@@H](CO9)O)O)O)OC(=O)C)C |
