Acyl Carrier Protein (ACP) (65-74)

• CAT Number: I018924
• CAS Number: 66851-75-0
• Molecular Formula: C₄₇H₇₄N₁₂O₁₆
• Molecular Weight: 1063.16
• Purity: ≥95%
• Target: Peptide and Derivatives
• IUPAC Name: (3S)-3-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-oxopentanoyl]amino]propanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-4-[[(2S)-1-[[(2S,3S)-1-[[(2S)-4-amino-1-(carboxymethylamino)-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
• InChI: InChI=1S/C47H74N12O16/c1-9-22(5)37(58-40(68)25(8)52-39(67)24(7)53-42(70)28(15-16-32(48)61)54-45(73)36(50)21(3)4)46(74)57-31(19-34(63)64)43(71)55-29(17-26-11-13-27(60)14-12-26)44(72)59-38(23(6)10-2)47(75)56-30(18-33(49)62)41(69)51-20-35(65)66/h11-14,21-25,28-31,36-38,60H,9-10,15-20,50H2,1-8H3,(H2,48,61)(H2,49,62)(H,51,69)(H,52,67)(H,53,70)(H,54,73)(H,55,71)(H,56,75)(H,57,74)(H,58,68)(H,59,72)(H,63,64)(H,65,66)/t22-,23-,24-,25-,28-,29-,30-,31-,36-,37-,38-/m0/s1
• InChIKey: OBUGXZVDQXDGTF-VEJNRXSDSA-N
• SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)NCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](C(C)C)N

Acyl Carrier Protein (ACP) (65-74)(CAT: I018924) is a peptide fragment integral to the fatty acid synthesis pathway, representing a key region involved in the transfer of acyl intermediates. This sequence is essential for interactions with enzymes such as ketosynthases and thioesterases, facilitating efficient fatty acid elongation. ACP (65-74) is widely studied in biochemical research to investigate protein-protein interactions, enzymatic mechanisms, and post-translational modifications, particularly phosphopantetheinylation, which activates ACP. It serves as a model for understanding ACP’s role in metabolic regulation, supporting the development of inhibitors targeting fatty acid biosynthesis in bacteria and other organisms, with potential therapeutic applications.