AD-mix-β

• CAT Number: R024248
• CAS Number: 148618-32-0
• Molecular Formula: C48H54N6O4
• Molecular Weight: 779.00
• Purity: ≥95%
• Synonyms: AD-mix-beta
• Storage: RT
• IUPAC Name: 4-[(S)-[(2S,4R,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methoxy]-1-[(R)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methoxy]phthalazine
• InChI: InChI=1S/C48H54N6O4/c1-5-29-27-53-21-17-31(29)23-43(53)45(35-15-19-49-41-13-11-33(55-3)25-39(35)41)57-47-37-9-7-8-10-38(37)48(52-51-47)58-46(44-24-32-18-22-54(44)28-30(32)6-2)36-16-20-50-42-14-12-34(56-4)26-40(36)42/h7-16,19-20,25-26,29-32,43-46H,5-6,17-18,21-24,27-28H2,1-4H3/t29-,30-,31-,32+,43+,44-,45+,46-/m0/s1
• InChIKey: YUCBLVFHJWOYDN-SOBQURILSA-N
• SMILES: CCC1CN2CCC1CC2C(C3=C4C=C(C=CC4=NC=C3)OC)OC5=NN=C(C6=CC=CC=C65)OC(C7CC8CCN7CC8CC)C9=C1C=C(C=CC1=NC=C9)OC

AD-mix-β（Cat No.:R024248）is a commercially available reagent mixture used in asymmetric dihydroxylation, a key reaction in organic synthesis for converting alkenes into vicinal diols with high enantioselectivity. It consists of potassium osmate, a chiral ligand (often a derivative of hydroquinine), and a co-oxidant, typically potassium ferricyanide. AD-mix-β is specifically designed to produce dihydroxylation products with the opposite enantiomeric excess compared to AD-mix-α. This reagent is essential in synthesizing chiral molecules for pharmaceuticals, agrochemicals, and fine chemicals, enabling precise control over stereochemistry.