Adefovir Dipivoxil

• CAT Number: A000851
• CAS Number: 142340-99-6
• Molecular Formula: C20H32N5O8P
• Molecular Weight: 501.47
• Purity: ≥95%
• Synonyms: 142340-99-6; Hepsera; Preveon; Adefovir pivoxil; Bis-POM PMEA
• Target: Metabolic Enzyme/Protease
• Solubility: >18.7mg/mL in DMSO
• Storage: -20°C
• InChI: InChI=1S/C20H32N5O8P/c1-19(2,3)17(26)30-11-32-34(28,33-12-31-18(27)20(4,5)6)13-29-8-7-25-10-24-14-15(21)22-9-23-16(14)25/h9-10H,7-8,11-13H2,1-6H3,(H2,21,22,23)
• InChIKey: WOZSCQDILHKSGG-UHFFFAOYSA-N
• SMILES: CC(C)(C)C(=O)OCOP(=O)(COCCN1C=NC2=C1N=CN=C2N)OCOC(=O)C(C)(C)C

Adefovir Dipivoxil（Cat No.:A000851）is an antiviral prodrug primarily used to treat chronic hepatitis B virus (HBV) infection. Once ingested, it is converted into its active form, adefovir, which inhibits viral DNA polymerase, preventing HBV replication and reducing viral load in the liver. This action helps decrease liver damage and the risk of developing cirrhosis or liver cancer. Known for its efficacy against lamivudine-resistant HBV strains, Adefovir Dipivoxil is valued in antiviral therapy regimens. With a favorable safety profile, it provides an essential option in long-term hepatitis B management.

Reference

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