Adenosine 5'-diphosphate sodium salt

• CAT Number: I018197
• CAS Number: 20398-34-9
• Molecular Formula: C₁₀H₁₅N₅O₁₀P₂.xNa
• Purity: ≥95%
• Target: Endogenous Metabolite
• Storage: -20°C

Adenosine 5′-diphosphate (ADP) sodium salt（Cat No.:I018197） is a nucleoside diphosphate that serves as a product of ATP dephosphorylation by ATPases. When present, it induces the aggregation of human platelets, playing a role in platelet activation and clot formation. Additionally, ADP sodium salt inhibits stimulated adenylate cyclase, primarily by interacting with P2T-purinoceptors. These purinoceptors are involved in various cellular signaling pathways, including those related to platelet activation and inhibition. The actions of ADP sodium salt highlight its importance in physiological processes and its involvement in platelet function and regulation.

Reference

[1]. Arts IC, et al. Adenosine 5′-triphosphate (ATP) supplements are not orally bioavailable: a randomized, placebo-controlled cross-over trial in healthy humans. J Int Soc Sports Nutr. 2012 Apr 17;9(1):16.[2]. Noel J. Cusack, et al. Effects of phosphate-modified analogs of adenosine 5′-diphosphate and adenosine 5′‐triphosphate at P2T-purinoceptors mediating human platelet activation by ADP. April 1996.[3]. Adenosine-5′-diphosphate