ADENOSINE-5'-DIPHOSPHOGLUCOSE

• CAT Number: M009690
• CAS Number: 102129-65-7
• Molecular Formula: C16H24N5O15P2 • 2Na
• Molecular Weight: 634.3
• Purity: ≥95%
• Synonyms: Adenosine-5′-diphosphoglucose ​;ADPG
• Storage: -20°C
• InChI: InChI=1S/C16H25N5O15P2.2Na/c17-13-7-14(19-3-18-13)21(4-20-7)15-11(26)9(24)6(33-15)2-32-37(28,29)36-38(30,31)35-16-12(27)10(25)8(23)5(1-22)34-16;;/h3-6,8-12,15-16,22-27H,1-2H2,(H,28,29)(H,30,31)(H2,17,18,19);;/q;2*+1/p-2/t5-,6-,8-,9-,10+,11-,12-,15-,1
• InChIKey: GZBIVALVIPYODS-LNXGRUPOSA-L
• SMILES: O[C@H]1[C@H](N2C=NC3=C2N=CN=C3N)O[C@H](COP(OP(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)([O-])=O)([O-])=O)[C@H]1O.[Na+].[Na+]

ADP-Glucose (ADPG; CAS 102129-65-7) is an immediate precursor used in the biosynthesis, by glucose addition, of storage polysaccharides in plants, green algae, and cyanobacteria, as well as structural polysaccharides in certain bacteria. It is used by amylose synthases or starch synthases in plastids in the production of amylose, amylopectins, starch, and other polysaccharides. ADPG is normally generated within plastids, although it can be biosynthesized in the cytoplasm of certain grasses and imported into plastids by a membrane-bound transporter.

Reference

1.Ball, Steven G., and Matthew K. Morell. "From bacterial glycogen to starch: understanding the biogenesis of the plant starch granule." Annual review of plant biology 54.1 (2003): 207-233.
2.Sambou, Tounkang, et al. "Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice." Molecular microbiology 70.3 (2008): 762-774.
3.Comparot-Moss, Sylviane, and Kay Denyer. "The evolution of the starch biosynthetic pathway in cereals and other grasses." Journal of experimental botany 60.9 (2009): 2481-2492.