Adenosine, N-(1-methyl-2-phenylethyl)-, (R)-

• CAT Number: I014028
• CAS Number: 38594-96-6
• Molecular Formula: C19H23N5O4
• Molecular Weight: 385.42
• Purity: ≥95%
• Synonyms: Adenosine, N-(1-methyl-2-phenylethyl)-, (R)-; L-PIA; L-2-N6-(Phenylisopropyl)adenosine; TH 162; TH-162; TH162;;(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(((R)-1-phenylpropan-2-yl)amino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
• Target: Adenosine Receptor
• Solubility: Soluble in DMSO
• IUPAC Name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[[(2R)-1-phenylpropan-2-yl]amino]purin-9-yl]oxolane-3,4-diol
• InChI: InChI=1S/C19H23N5O4/c1-11(7-12-5-3-2-4-6-12)23-17-14-18(21-9-20-17)24(10-22-14)19-16(27)15(26)13(8-25)28-19/h2-6,9-11,13,15-16,19,25-27H,7-8H2,1H3,(H,20,21,23)/t11-,13-,15-,16-,19-/m1/s1
• InChIKey: RIRGCFBBHQEQQH-SSFGXONLSA-N
• SMILES: OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C(N=CN=C32)N[C@H](C)CC4=CC=CC=C4)O1)O)O

Adenosine, N-(1-methyl-2-phenylethyl)-, (R)- (Cat.No:I014028) is a chiral compound used in research as a selective adenosine A2A receptor agonist. It has been investigated for its potential therapeutic effects on conditions such as Parkinson’s disease and inflammation. The compound is also used as a tool in studying the adenosine A2A receptor and related signaling pathways.

Reference

1: Della Latta V, Cabiati M, Rocchiccioli S, Del Ry S, Morales MA. The role of the adenosinergic system in lung fibrosis. Pharmacol Res. 2013 Oct;76:182-9. doi: 10.1016/j.phrs.2013.08.004. Epub 2013 Aug 28. Review. PubMed PMID: 23994158.