For research use only. Not for therapeutic Use.
AdipoRon(CAT: I000029) is a synthetic small-molecule agonist of adiponectin receptors AdipoR1 and AdipoR2, which are involved in regulating glucose and lipid metabolism. By activating these receptors, AdipoRon mimics the effects of adiponectin, enhancing insulin sensitivity and improving energy homeostasis. It is particularly valuable in metabolic disease research, supporting studies on conditions such as type 2 diabetes, obesity, and cardiovascular diseases. AdipoRon provides a powerful tool for exploring the therapeutic potential of adiponectin receptor modulation and advancing drug discovery for metabolic disorders and related complications.
| Catalog Number | I000029 |
| CAS Number | 924416-43-3 |
| Synonyms | 2-(4-benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide |
| Molecular Formula | C27H28N2O3 |
| Purity | ≥95% |
| Target | Adiponectin Receptor |
| Solubility | DMSO: ≥ 44 mg/mL |
| Storage | Store at -20C |
| IC50 | 1.8/3.1 uM(AdipoR1/2, Kd) |
| IUPAC Name | 2-(4-benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide |
| InChI | InChI=1S/C27H28N2O3/c30-26(28-24-15-17-29(18-16-24)19-21-7-3-1-4-8-21)20-32-25-13-11-23(12-14-25)27(31)22-9-5-2-6-10-22/h1-14,24H,15-20H2,(H,28,30) |
| InChIKey | SHHUPGSHGSNPDB-UHFFFAOYSA-N |
| SMILES | O=C(C1=CC=C(OCC(NC2CCN(CC3=CC=CC=C3)CC2)=O)C=C1)C4=CC=CC=C4 |
