For research use only. Not for therapeutic Use.
Adropin (34-76)（Cat No.:I041257）is a peptide fragment derived from the full-length adropin protein, which is involved in regulating energy homeostasis, glucose metabolism, and cardiovascular function. The fragment corresponds to residues 34-76 of the human, mouse, and rat adropin sequence and retains some of the bioactive properties of the full peptide. Adropin has been shown to influence insulin sensitivity, promote fat oxidation, and support endothelial function. Its potential therapeutic applications include the treatment of metabolic disorders, obesity, and cardiovascular diseases, with ongoing research exploring its role in regulating energy balance and vascular health.
| CAS Number | 1802086-30-1 |
| Molecular Formula | C190H293N55O68S2 |
| Purity | ≥95% |
| IUPAC Name | (2S)-1-[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-5-amino-2-[[(2S)-1-[(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(6S,12S,15S,18S,21S,27S,30S,33S,36S,39S,42S,45S,48S,51S,54S,57S,60S,63S,66S,69R,74R,77S)-69-amino-18-(2-amino-2-oxoethyl)-60-(3-carbamimidamidopropyl)-33-(2-carboxyethyl)-45,51-bis(carboxymethyl)-12,15,27,30,36,42,57,63-octakis(hydroxymethyl)-66-(1H-imidazol-4-ylmethyl)-54-methyl-39-(2-methylpropyl)-2,5,11,14,17,20,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,76-docosaoxo-48-propan-2-yl-71,72-dithia-1,4,10,13,16,19,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,75-docosazatetracyclo[75.3.0.06,10.021,25]octacontane-74-carbonyl]pyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]hexanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-4-carboxybutanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-oxopentanoyl]pyrrolidine-2-carboxylic acid |
| InChI | InChI=1S/C190H293N55O68S2/c1-90(2)63-109(157(280)216-108(42-47-139(195)258)183(306)245-62-24-36-137(245)189(312)313)219-158(281)110(64-91(3)4)220-160(283)112(66-96-37-39-99(256)40-38-96)222-167(290)118(76-246)208-141(260)74-202-151(274)103(43-48-143(262)263)211-161(284)114(68-98-73-200-89-205-98)223-171(294)125(83-253)232-179(302)133-32-18-56-239(133)182(305)107(26-12-14-52-192)215-155(278)104(41-46-138(194)257)213-177(300)134-33-21-59-242(134)187(310)136-35-23-61-244(136)188(311)135-34-22-60-243(135)181(304)95(10)207-152(275)101(25-11-13-51-191)209-154(277)106(45-50-145(266)267)214-176(299)131-30-20-58-241(131)186(309)128-87-315-314-86-100(193)150(273)218-113(67-97-72-199-88-204-97)162(285)229-120(78-248)168(291)210-102(27-15-53-201-190(197)198)153(276)226-119(77-247)166(289)206-94(9)149(272)217-117(71-147(270)271)165(288)236-148(93(7)8)180(303)225-116(70-146(268)269)164(287)231-122(80-250)170(293)221-111(65-92(5)6)159(282)228-121(79-249)169(292)212-105(44-49-144(264)265)156(279)227-123(81-251)172(295)234-127(85-255)185(308)240-57-19-31-132(240)178(301)224-115(69-140(196)259)163(286)230-124(82-252)173(296)233-126(84-254)184(307)238-55-17-28-129(238)174(297)203-75-142(261)237-54-16-29-130(237)175(298)235-128/h37-40,72-73,88-95,100-137,148,246-256H,11-36,41-71,74-87,191-193H2,1-10H3,(H2,194,257)(H2,195,258)(H2,196,259)(H,199,204)(H,200,205)(H,202,274)(H,203,297)(H,206,289)(H,207,275)(H,208,260)(H,209,277)(H,210,291)(H,211,284)(H,212,292)(H,213,300)(H,214,299)(H,215,278)(H,216,280)(H,217,272)(H,218,273)(H,219,281)(H,220,283)(H,221,293)(H,222,290)(H,223,294)(H,224,301)(H,225,303)(H,226,276)(H,227,279)(H,228,282)(H,229,285)(H,230,286)(H,231,287)(H,232,302)(H,233,296)(H,234,295)(H,235,298)(H,236,288)(H,262,263)(H,264,265)(H,266,267)(H,268,269)(H,270,271)(H,312,313)(H4,197,198,201)/t94-,95-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,148-/m0/s1 |
| InChIKey | HSJJHNVPBLCAEH-PLGVNXRWSA-N |
| SMILES | C[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N3CCC[C@H]3C(=O)NCC(=O)N4CCC[C@H]4C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CO)CCCNC(=N)N)CO)CC5=CNC=N5)N)C(=O)N6CCC[C@H]6C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N7CCC[C@H]7C(=O)N8CCC[C@H]8C(=O)N9CCC[C@H]9C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)O)CO)CO)CC(=O)N)CO)CO)CCC(=O)O)CO)CC(C)C)CO)CC(=O)O)C(C)C)CC(=O)O |
