ADX-10061

• CAT Number: I001238
• CAS Number: 128022-68-4
• Molecular Formula: C19H20N2O4
• Molecular Weight: 340.38
• Purity: ≥95%
• Synonyms: ADX-10061; CEE-310; CEE-03-310; NNC-01-0687; NNC-687; ADX10061; CEE310; CEE03310; NNC010687; NNC687; ADX 10061; CEE 310; CEE 03 310; NNC 01 0687; NNC 687;(S)-5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol
• Target: dopamine D1 receptor antagonist
• Solubility: Soluble in DMSO
• Storage: 0 - 4°Cfor short term (days to weeks), or -20 °C for long term (months).
• IUPAC Name: (5S)-5-(2,3-dihydro-1-benzofuran-7-yl)-3-methyl-8-nitro-1,2,4,5-tetrahydro-3-benzazepin-7-ol
• InChI: InChI=1S/C19H20N2O4/c1-20-7-5-13-9-17(21(23)24)18(22)10-15(13)16(11-20)14-4-2-3-12-6-8-25-19(12)14/h2-4,9-10,16,22H,5-8,11H2,1H3/t16-/m1/s1
• InChIKey: XZPSYCOYKJRHKE-MRXNPFEDSA-N
• SMILES: CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC4=C3OCC4)O)[N+](=O)[O-]

ADX-10061（Cat No.:I001238）is a selective antagonist of the 5-HT2B receptor, used primarily in research focused on cardiovascular and fibrotic diseases. By blocking the 5-HT2B receptor, it inhibits serotonin-induced fibroblast proliferation and tissue fibrosis, making it a valuable compound for studying conditions like pulmonary hypertension and heart failure. Its high specificity and potency ensure reliable results in preclinical studies, aiding in the development of new therapeutic approaches. ADX-10061 contributes significantly to understanding the role of serotonin in fibrosis and advancing treatments for related cardiovascular conditions.