For research use only. Not for therapeutic Use.
AEG 3482(Cat No.:I010598), also known as azoxymethane (AOM), is a mutagenic and carcinogenic compound commonly used in preclinical research to induce colorectal tumors in animal models. It is a DNA-alkylating agent that specifically targets colonic epithelial cells, leading to the formation of DNA adducts and subsequent tumor development. AEG 3482 has been widely employed in studies investigating the mechanisms of colorectal cancer initiation and progression, as well as the evaluation of potential therapeutic interventions for this disease.
Catalog Number | I010598 |
CAS Number | 63735-71-7 |
Synonyms | 6-Phenylimidazo[2,1-b]-1,3,4-thiadiazole-2-sulfonamide |
Molecular Formula | C10H8N4O2S2 |
Purity | ≥95% |
Target | Apoptosis |
Solubility | Soluble to 100 mM in DMSO and to 5 mM in ethanol |
Storage | Store at RT |
IUPAC Name | 6-phenylimidazo[2,1-b][1,3,4]thiadiazole-2-sulfonamide |
InChI | InChI=1S/C10H8N4O2S2/c11-18(15,16)10-13-14-6-8(12-9(14)17-10)7-4-2-1-3-5-7/h1-6H,(H2,11,15,16) |
InChIKey | MQUYTXDAVCOCMX-UHFFFAOYSA-N |
SMILES | C1=CC=C(C=C1)C2=CN3C(=N2)SC(=N3)S(=O)(=O)N |