For research use only. Not for therapeutic Use.
Afatinib Impurity AFT-8(CAT: C000024) holds significance in pharmaceutical chemistry and drug characterization. It is recognized as an impurity that arises from the synthesis or storage of Afatinib, a quinazoline derivative used in the treatment of various cancers and respiratory diseases. Understanding impurities like AFT-8 is crucial for ensuring the quality, safety, and efficacy of the parent compound.
| Catalog Number | C000024 |
| CAS Number | 2323570-72-3 |
| Synonyms | N-[4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutenamide; |
| Molecular Formula | C₂₄H₂₇ClFN₅O₄ |
| Purity | ≥95% |
| Solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated) |
| Appearance | White to Off-White Solid |
| Storage | 4°C, Inert atmosphere |
| Reference | Nakao, K., et al.: Sci. Rep., 9, 18202 (2019); Ebert, K, PLoS One, 14, 0223225 (2019) |
