AFN-1252 tosylate

• CAT Number: I021478
• CAS Number: 1047981-31-6
• Molecular Formula: CC29H29N3O6S
• Molecular Weight: 547.63
• Purity: 98%
• Synonyms: AFN-1252 tosylate; API-1252 tosylate
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 2-Propenamide, N-methyl-N-((3-methyl-2-benzofuranyl)methyl)-3-(5,6,7,8-tetrahydro-7-oxo-1,8-naphthyridin-3-yl)-, (2E)-, 4-methylbenzenesulfonate (1:1)
• InChI: InChI=1S/C22H21N3O3.C7H8O3S/c1-14-17-5-3-4-6-18(17)28-19(14)13-25(2)21(27)10-7-15-11-16-8-9-20(26)24-22(16)23-12-15;1-6-2-4-7(5-3-6)11(8,9)10/h3-7,10-12H,8-9,13H2,1-2H3,(H,23,24,26);2-5H,1H3,(H,8,9,10)/b10-7+
• InChIKey: NHTYVWVPSCBFQW-HCUGZAAXSA-N
• SMILES: O=C(N(C)CC1=C(C)C2=CC=CC=C2O1)/C=C/C3=CC(CC4)=C(N=C3)NC4=O.O=S(C5=CC=C(C)C=C5)(O)=O

AFN-1252 Tosylate(CAT: I021478) is a potent and selective inhibitor of bacterial enoyl-acyl carrier protein reductase (FabI), a key enzyme in fatty acid biosynthesis. This high-purity compound is primarily utilized in research on antimicrobial resistance and the development of targeted antibiotics. By specifically targeting FabI, AFN-1252 Tosylate exhibits strong activity against Gram-positive pathogens, including Staphylococcus aureus. Its precision and efficacy make it ideal for studying bacterial fatty acid metabolism and testing novel therapeutic approaches. Suitable for in vitro and in vivo experiments, AFN-1252 Tosylate supports advanced microbiological research and the pursuit of innovative antibacterial treatments.